Inhalations in the Treatment of Diseases of the Respiratory Passages by Jacob Mendes Da CostaCall Number: RM161 .D11 2010
ISBN: 9780217490221
Publication Date: 2009-08-01
Purchase of this book includes free trial access to www.million-books.com where you can read more than a million books for free. This is an OCR edition with typos. Excerpt from book: CHAPTER III. THE PENETRABILITY OF ATOMIZED FLUIDS INTO THE AIR-PASSAGES. In the preceding considerations, and while discussing the mode of applying the medicated spray, it has been assumed that this can be made to reach not only the fauces and pharynx, but the respiratory channels. Now, with reference to the former point there can be no question; but much skepticism has prevailed as regards the entrance into the air tubes of the pulverized fluids; and before passing on to indicate the uses of these agents, it is incumbent to inquire into the evidence on which it has been assumed that they penetrate into the lungs, or even into the larynx. Not to mention further the well-known facts alluded to in connection with the coal miner's lung, and which have a strong bearing on the subject, the evidence of fine particles reaching the air-passages is of two kinds: first, that furnished by demonstrative experiments made on animals and man; and, secondly, that attained by perceiving the effects of inhaling the atomized liquid, particularly its prompt effect in producing or allaying spasm, in checking hemorrhage and the like. To the first category belong the interesting experiments of Demarquay, which, repeated in the presence of Poggiale, were used by him as the basis of his able report to the French Academy. Dogs and rabbits, with their mouths forced open and their nostrils closed, were made to inhale for five minutes a pulverized solution of perchloride of iron, of the strength of 1 part of the iron to 100 of distilled water. The animals were afterward killed, and throughout the larynx, trachea, bronchial tubes, and even in the lung structure, the presence of the persalt of iron was clearly detected by the production of Prussian blue with the ferrocyanide of potassium and acetic aci...